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Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC

Gap-junctional channels, permeable to large hydrophilic solutes of up to M(r) ≈ 1,000, are responsible for cell-to-cell communication. Phosphorylation of connexin 43 (Cx43) by PKC abolishes the permeability of gap-junctional channels and hemichannels to large hydrophilic solutes, but not to small in...

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Autors principals: Bao, Xiaoyong, Lee, Sung Chang, Reuss, Luis, Altenberg, Guillermo A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817834/
https://ncbi.nlm.nih.gov/pubmed/17360407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603154104
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