The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells

The efficient treatment of hematological malignancies as Acute Myeloid Leukemia, myelofibrosis and Chronic Myeloid Leukemia, requires the elimination of cancer-initiating cells and the prevention of disease relapse through targeting pathways that stimulate generation and maintenance of these cells....

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Giordani, Giorgia, Barraco, Marilena, Giangrande, Angela, Martinelli, Giovanni, Guadagnuolo, Viviana, Simonetti, Giorgia, Perini, Giovanni, Bernardoni, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342419/
https://ncbi.nlm.nih.gov/pubmed/27486815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10879
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