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The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells

The efficient treatment of hematological malignancies as Acute Myeloid Leukemia, myelofibrosis and Chronic Myeloid Leukemia, requires the elimination of cancer-initiating cells and the prevention of disease relapse through targeting pathways that stimulate generation and maintenance of these cells....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Giordani, Giorgia, Barraco, Marilena, Giangrande, Angela, Martinelli, Giovanni, Guadagnuolo, Viviana, Simonetti, Giorgia, Perini, Giovanni, Bernardoni, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342419/
https://ncbi.nlm.nih.gov/pubmed/27486815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10879
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