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Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells

Glutamine provides cancer cells with the energy required to synthesize macromolecules. Methods which block glutamine metabolism in treatment of breast cancer inhibit oncogenic transformation and tumor growth. We investigated whether inhibiting glutamine metabolism produces effects that are synergist...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Chen, Lian, Cui, Hengmin, Fang, Jing, Deng, Huidan, Kuang, Ping, Guo, Hongrui, Wang, Xun, Zhao, Ling
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342373/
https://ncbi.nlm.nih.gov/pubmed/27419628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10579
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