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Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells

Glutamine provides cancer cells with the energy required to synthesize macromolecules. Methods which block glutamine metabolism in treatment of breast cancer inhibit oncogenic transformation and tumor growth. We investigated whether inhibiting glutamine metabolism produces effects that are synergist...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Lian, Cui, Hengmin, Fang, Jing, Deng, Huidan, Kuang, Ping, Guo, Hongrui, Wang, Xun, Zhao, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342373/
https://ncbi.nlm.nih.gov/pubmed/27419628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10579
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