Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi

The development of new adjuvants enables fine modulation of the elicited immune responses. Ideally, the use of one or more adjuvants should result in the induction of a protective immune response against the specific pathogen. We have evaluated the immune response and protection against Trypanosoma...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Matos, Marina N., Cazorla, Silvia I., Schulze, Kai, Ebensen, Thomas, Guzmán, Carlos A., Malchiodi, Emilio L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342303/
https://ncbi.nlm.nih.gov/pubmed/28234897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005300
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