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Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches

Influenza viruses have acquired resistance to approved neuraminidase-targeting drugs, increasing the need for new drug targets for the development of novel anti-influenza drugs. Nucleoprotein (NP) is an attractive target since it has an indispensable role in virus replication and its amino acid sequ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Makau, Juliann Nzembi, Watanabe, Ken, Ishikawa, Takeshi, Mizuta, Satoshi, Hamada, Tsuyoshi, Kobayashi, Nobuyuki, Nishida, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342234/
https://ncbi.nlm.nih.gov/pubmed/28273150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173582
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