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Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion

Leukocyte trafficking is crucial to facilitate efficient immune responses. Here, we report that the large GTPase dynamin2, which is generally considered to have a key role in endocytosis and membrane remodeling, is an essential regulator of integrin-dependent human T lymphocyte adhesion and migratio...

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Vydáno v:PLoS One
Hlavní autoři: Eppler, Felix J., Quast, Thomas, Kolanus, Waldemar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342215/
https://ncbi.nlm.nih.gov/pubmed/28273099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172443
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