LSC ACTIVITY IS CONTROLLED BY OLIGOMERIZATION AND REGULATES INTEGRIN ADHESION

Lsc is a hematopoietic-restricted protein that functions as an effector of Gα(12/13-)associated G-protein coupled receptors that activates RhoA. In the absence of Lsc leukocytes exhibit impaired migration and B lymphocytes inefficiently resolve integrin-mediated adhesion. Here, we demonstrate that L...

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Hauptverfasser: Hu, Jiancheng, Strauch, Pamela, Rubtsov, Anatoly, Donovan, Erin E., Pelanda, Roberta, Torres, Raul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2315659/
https://ncbi.nlm.nih.gov/pubmed/18157933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.11.002
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