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Addressing intra-tumoral heterogeneity and therapy resistance

In the last several years, our appreciation of intra-tumoral heterogeneity has greatly increased due to accumulating evidence for the co-existence of genetically and epigenetically divergent cancer cells residing in different microenvironments within a tumor. Herein, we review recent literature disc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rybinski, Brad, Yun, Kyuson
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342165/
https://ncbi.nlm.nih.gov/pubmed/27608848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11875
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