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18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

18β-glycyrrhetinic acid (GRA) exerts anti-tumor effects on various types of cancer. In the present study, we found that GRA attenuated the severity of gastritis and suppressed gastric tumorigenesis in transgenic mice. We also discovered that miR-149-3p was downregulated in gastric cancer tissues and...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Cao, Donghui, Jia, Zhifang, You, Lili, Wu, Yanhua, Hou, Zhen, Suo, Yueer, Zhang, Houjun, Wen, Simin, Tsukamoto, Tetsuya, Oshima, Masanobu, Jiang, Jing, Cao, Xueyuan
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342136/
https://ncbi.nlm.nih.gov/pubmed/27713126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12443
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