18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

18β-glycyrrhetinic acid (GRA) exerts anti-tumor effects on various types of cancer. In the present study, we found that GRA attenuated the severity of gastritis and suppressed gastric tumorigenesis in transgenic mice. We also discovered that miR-149-3p was downregulated in gastric cancer tissues and...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Cao, Donghui, Jia, Zhifang, You, Lili, Wu, Yanhua, Hou, Zhen, Suo, Yueer, Zhang, Houjun, Wen, Simin, Tsukamoto, Tetsuya, Oshima, Masanobu, Jiang, Jing, Cao, Xueyuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342136/
https://ncbi.nlm.nih.gov/pubmed/27713126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12443
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