18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling

18β-glycyrrhetinic acid (GRA) exerts anti-tumor effects on various types of cancer. In the present study, we found that GRA attenuated the severity of gastritis and suppressed gastric tumorigenesis in transgenic mice. We also discovered that miR-149-3p was downregulated in gastric cancer tissues and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cao, Donghui, Jia, Zhifang, You, Lili, Wu, Yanhua, Hou, Zhen, Suo, Yueer, Zhang, Houjun, Wen, Simin, Tsukamoto, Tetsuya, Oshima, Masanobu, Jiang, Jing, Cao, Xueyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342136/
https://ncbi.nlm.nih.gov/pubmed/27713126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12443
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