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Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells
Anti-estrogen treatment, exemplified by tamoxifen, is a well-established adjuvant therapy for estrogen receptor alpha (ERα)-positive breast cancer. However, the effectiveness of this drug is limited due to the development of resistance. The Hedgehog (HH) signaling pathway is critical in embryonic de...
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| I publikationen: | Oncotarget |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Impact Journals LLC
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342103/ https://ncbi.nlm.nih.gov/pubmed/27689403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12259 |
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