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Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway

miR122 is the prevalent miRNA in adult healthy liver and it is responsible for liver stem cell differentiation towards hepatocyte lineage. Its expression is frequently lost in hepatocellular carcinoma (HCC). We studied the effects of restoring miR122 expression in a distinctive cell line derived fro...

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Publicat a:Oncotarget
Autors principals: Boix, Loreto, López-Oliva, Juan Manuel, Rhodes, Ana Carolina, Bruix, Jordi
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342080/
https://ncbi.nlm.nih.gov/pubmed/27612430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11885
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