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Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway

miR122 is the prevalent miRNA in adult healthy liver and it is responsible for liver stem cell differentiation towards hepatocyte lineage. Its expression is frequently lost in hepatocellular carcinoma (HCC). We studied the effects of restoring miR122 expression in a distinctive cell line derived fro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boix, Loreto, López-Oliva, Juan Manuel, Rhodes, Ana Carolina, Bruix, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342080/
https://ncbi.nlm.nih.gov/pubmed/27612430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11885
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