Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

Local acidosis is a common feature of allergic, vascular, autoimmune, and cancer diseases. However, few studies have addressed the effect of extracellular pH on the immune response. Here, we analyzed whether low pH could modulate complement-dependent cytotoxicity (CDC) against IgG-coated cells. Usin...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Dantas, Ezequiel, Díaz, Fernando Erra, Gerber, Pehuén Pereyra, Merlotti, Antonela, Varese, Augusto, Ostrowski, Matías, Sabatté, Juan, Geffner, Jorge
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342046/
https://ncbi.nlm.nih.gov/pubmed/27716623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12412
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