Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

Local acidosis is a common feature of allergic, vascular, autoimmune, and cancer diseases. However, few studies have addressed the effect of extracellular pH on the immune response. Here, we analyzed whether low pH could modulate complement-dependent cytotoxicity (CDC) against IgG-coated cells. Usin...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Dantas, Ezequiel, Díaz, Fernando Erra, Gerber, Pehuén Pereyra, Merlotti, Antonela, Varese, Augusto, Ostrowski, Matías, Sabatté, Juan, Geffner, Jorge
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342046/
https://ncbi.nlm.nih.gov/pubmed/27716623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12412
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