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Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

Local acidosis is a common feature of allergic, vascular, autoimmune, and cancer diseases. However, few studies have addressed the effect of extracellular pH on the immune response. Here, we analyzed whether low pH could modulate complement-dependent cytotoxicity (CDC) against IgG-coated cells. Usin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dantas, Ezequiel, Díaz, Fernando Erra, Gerber, Pehuén Pereyra, Merlotti, Antonela, Varese, Augusto, Ostrowski, Matías, Sabatté, Juan, Geffner, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342046/
https://ncbi.nlm.nih.gov/pubmed/27716623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12412
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