Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

Overexpression of Mcl-1 is implicated in resistance of several cancers to chemotherapeutic treatment, therefore identifying a safe way to decrease its expression in tumor cells represents a central goal. We investigated if a modulation of the diet could impact on Mcl-1 expression using a Myc-driven...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rubio-Patiño, Camila, Bossowski, Jozef P., Villa, Elodie, Mondragón, Laura, Zunino, Barbara, Proïcs, Emma, Chiche, Johanna, Bost, Frédéric, Verhoeyen, Els, Ricci, Jean-Ehrland
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341978/
https://ncbi.nlm.nih.gov/pubmed/27689327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12309
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