Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential

The prostanoid thromboxane (TX) A(2) plays a central role in haemostasis and is increasingly implicated in cancer progression. TXA(2) signals through two T Prostanoid receptor (TP) isoforms termed TPα and TPβ, with both encoded by the TBXA2R gene. Despite exhibiting several functional and regulatory...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Mulvaney, Eamon P., Shilling, Christine, Eivers, Sarah B., Perry, Antoinette S., Bjartell, Anders, Kay, Elaine W., Watson, R. William, Kinsella, B. Therese
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341971/
https://ncbi.nlm.nih.gov/pubmed/27689401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12256
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