Proteomic analysis uncovers common effects of IFN-γ and IL-27 on the HLA class I antigen presentation machinery in human cancer cells

IL-27, a member of the IL-12-family of cytokines, has shown anti-tumor activity in several pre-clinical models due to anti-proliferative, anti-angiogenic and immune-enhancing effects. On the other hand, IL-27 demonstrated immune regulatory activities and inhibition of auto-immunity in mouse models....

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Petretto, Andrea, Carbotti, Grazia, Inglese, Elvira, Lavarello, Chiara, Pistillo, Maria Pia, Rigo, Valentina, Croce, Michela, Longo, Luca, Martini, Stefania, Vacca, Paola, Ferrini, Silvano, Fabbi, Marina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper: Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341926/
https://ncbi.nlm.nih.gov/pubmed/27683036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12235
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