Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response

Tuberculosis, caused by Mycobacterium tuberculosis (MTB) infection, remains a grave global public health burden which claims the lives around two to three million annually. PE and PPE proteins, featured by the Pro-Glu (PE) or Pro-Pro-Glu (PPE) motifs at the conserved N-terminal domain, are abundant...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Deng, Wanyan, Yang, Wenmin, Zeng, Jie, Abdalla, Abualgasim Elgaili, Xie, Jianping
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341880/
https://ncbi.nlm.nih.gov/pubmed/27634911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12030
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