ロード中...

Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

In prior work we reported that advanced stage, drug-resistant pancreatic cancer cells (the SW1990 line) can be sensitized to the EGFR-targeting tyrosine kinase inhibitors (TKIs) erlotinib and gefitinib by treatment with 1,3,4-O-Bu(3)ManNAc (Bioorg. Med. Chem. Lett. (2015) 25(6):1223-7). Here we prov...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Mathew, Mohit P., Tan, Elaine, Saeui, Christopher T., Bovonratwet, Patawut, Sklar, Samuel, Bhattacharya, Rahul, Yarema, Kevin J.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341816/
https://ncbi.nlm.nih.gov/pubmed/27613843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11582
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!