Sonic hedgehog pathway activation increases mitochondrial abundance and activity in hippocampal neurons

Mitochondria are essential organelles whose biogenesis, structure, and function are regulated by many signaling pathways. We present evidence that, in hippocampal neurons, activation of the Sonic hedgehog (Shh) signaling pathway affects multiple aspects of mitochondria. Mitochondrial mass was increa...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Yao, Pamela J., Manor, Uri, Petralia, Ronald S., Brose, Rebecca D., Wu, Ryan T. Y., Ott, Carolyn, Wang, Ya-Xian, Charnoff, Ari, Lippincott-Schwartz, Jennifer, Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341723/
https://ncbi.nlm.nih.gov/pubmed/27932496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-07-0553
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