Association between functional polymorphisms in the promoter of the miR-143/145 cluster and risk of intracranial aneurysm

MicroRNAs (miRs)-143/145 are involved in various biological processes related to aneurysm formation and are downregulated in patients with intracranial aneurysm (IA). We aimed to determine whether two functional polymorphisms (i.e. rs4705342 and rs4705343) in the promoter of miR-143/145 are related...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sima, Xiutian, Sun, Hong, Zhou, Peizhi, You, Chao, Cai, Bowen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341556/
https://ncbi.nlm.nih.gov/pubmed/28272526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43633
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