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Deletion of the miR-143/145 Cluster Leads to Hydronephrosis in Mice

Obstructive nephropathy, the leading cause of kidney failure in children, can be anatomic or functional. The underlying causes of functional hydronephrosis are not well understood. miRNAs, which are small noncoding RNAs, regulate gene expression at the post-transcriptional level. We found that miR-1...

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Библиографические подробности
Опубликовано в: :Am J Pathol
Главные авторы: Medrano, Silvia, Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258506/
https://ncbi.nlm.nih.gov/pubmed/25307343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.012
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