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Deletion of the miR-143/145 Cluster Leads to Hydronephrosis in Mice

Obstructive nephropathy, the leading cause of kidney failure in children, can be anatomic or functional. The underlying causes of functional hydronephrosis are not well understood. miRNAs, which are small noncoding RNAs, regulate gene expression at the post-transcriptional level. We found that miR-1...

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Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Medrano, Silvia, Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258506/
https://ncbi.nlm.nih.gov/pubmed/25307343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.012
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