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Deletion of the miR-143/145 Cluster Leads to Hydronephrosis in Mice

Obstructive nephropathy, the leading cause of kidney failure in children, can be anatomic or functional. The underlying causes of functional hydronephrosis are not well understood. miRNAs, which are small noncoding RNAs, regulate gene expression at the post-transcriptional level. We found that miR-1...

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Detalles Bibliográficos
Publicado en:Am J Pathol
Autores principales: Medrano, Silvia, Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258506/
https://ncbi.nlm.nih.gov/pubmed/25307343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.012
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