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The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4(WDTC) (1) E3 ligase
WDTC1/Adp encodes an evolutionarily conserved suppressor of lipid accumulation. While reduced WDTC1 expression is associated with obesity in mice and humans, its cellular function is unknown. Here, we demonstrate that WDTC1 is a component of a DDB1‐CUL4‐ROC1 (CRL4) E3 ligase. Using 3T3‐L1 cell cultu...
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| Vydáno v: | EMBO Rep |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341520/ https://ncbi.nlm.nih.gov/pubmed/27113764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540500 |
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