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Induced regulatory T cells are phenotypically unstable and do not protect mice from rapidly progressive glomerulonephritis

Regulatory T (Treg) cells are a suppressive CD4(+) T‐cell subset. We generated induced Treg (iTreg) cells and explored their therapeutic potential in a murine model of rapidly progressive glomerulonephritis. Polyclonal naive CD4(+) T cells were cultured in vitro with interleukin‐2 (IL‐2), transformi...

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Bibliografiske detaljer
Udgivet i:Immunology
Main Authors: Ghali, Joanna R., Alikhan, Maliha A., Holdsworth, Stephen R., Kitching, A. Richard
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341499/
https://ncbi.nlm.nih.gov/pubmed/27606831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12671
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