Celastrol prevents cadmium‐induced neuronal cell death by blocking reactive oxygen species‐mediated mammalian target of rapamycin pathway

BACKGROUND AND PURPOSE: Increasing evidence has suggested cadmium (Cd), as an inducer of ROS, is a potential pathogenic factor in human neurodegenerative diseases. Thus, it is important to find effective interventions for Cd‐induced oxidative stress in the CNS. Here, we have studied the effects of c...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Zhang, Ruijie, Zhang, Nana, Zhang, Hai, Liu, Chunxiao, Dong, Xiaoqing, Wang, Xiaoxue, Zhu, Yu, Xu, Chong, Liu, Lei, Yang, Sijun, Huang, Shile, Chen, Long
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341486/
https://ncbi.nlm.nih.gov/pubmed/27764525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13655
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