Comparative proteomics of a model MCF10A-KRas(G12V) cell line reveals a distinct molecular signature of the KRas(G12V) cell surface

Oncogenic Ras mutants play a major role in the etiology of most aggressive and deadly carcinomas in humans. In spite of continuous efforts, effective pharmacological treatments targeting oncogenic Ras isoforms have not been developed. Cell-surface proteins represent top therapeutic targets primarily...

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Publicado en:Oncotarget
Main Authors: Ye, Xiaoying, Chan, King C., Waters, Andrew M., Bess, Matthew, Harned, Adam, Wei, Bih-Rong, Loncarek, Jadranka, Luke, Brian T., Orsburn, Benjamin C., Hollinger, Bradley D., Stephens, Robert M., Bagni, Rachel, Martinko, Alex, Wells, James A., Nissley, Dwight V., McCormick, Frank, Whiteley, Gordon, Blonder, Josip
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341332/
https://ncbi.nlm.nih.gov/pubmed/27894102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13566
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