Fenofibrate inhibits atrial metabolic remodelling in atrial fibrillation through PPAR‐α/sirtuin 1/PGC‐1α pathway

BACKGROUND AND PURPOSE: Atrial metabolic remodelling is critical for the process of atrial fibrillation (AF). The PPAR‐α/sirtuin 1 /PPAR co‐activator α (PGC‐1α) pathway plays an important role in maintaining energy metabolism. However, the effect of the PPAR‐α agonist fenofibrate on AF is unclear. T...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Liu, Guang‐zhong, Hou, Ting‐ting, Yuan, Yue, Hang, Peng‐zhou, Zhao, Jing‐jing, Sun, Li, Zhao, Guan‐qi, Zhao, Jing, Dong, Jing‐mei, Wang, Xiao‐bing, Shi, Hang, Liu, Yong‐wu, Zhou, Jing‐hua, Dong, Zeng‐xiang, Liu, Yang, Zhan, Cheng‐chuang, Li, Yue, Li, Wei‐min
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341245/
https://ncbi.nlm.nih.gov/pubmed/26787506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13438
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