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Prostaglandin E(2) inhibits neutrophil extracellular trap formation through production of cyclic AMP
BACKGROUND AND PURPOSE: Upon stimulation, neutrophils release their nuclear contents called neutrophil extracellular traps (NETs), which contain unfolded chromatin and lysosomal enzymes. NETs have been demonstrated to play a critical role in host defence, although the role of PGE(2), a bioactive sub...
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| 發表在: | Br J Pharmacol |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341226/ https://ncbi.nlm.nih.gov/pubmed/26505736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13373 |
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