Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways

BACKGROUND: Inflammatory breast cancer (IBC), a particularly aggressive form of breast cancer, is characterized by cancer stem cell (CSC) phenotype. Due to a lack of targeted therapies, the identification of molecular markers of IBC is of major importance. The heparan sulfate proteoglycan Syndecan-1...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ibrahim, Sherif Abdelaziz, Gadalla, Ramy, El-Ghonaimy, Eslam A., Samir, Omnia, Mohamed, Hossam Taha, Hassan, Hebatallah, Greve, Burkhard, El-Shinawi, Mohamed, Mohamed, Mona Mostafa, Götte, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341174/
https://ncbi.nlm.nih.gov/pubmed/28270211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0621-z
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