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Inflammatory breast cancer: Activation of the aryl hydrocarbon receptor and its target CYP1B1 correlates closely with Wnt5a/b-β-catenin signalling, the stem cell phenotype and disease progression

The aim of the present study was to evaluate the expression levels of the aryl hydrocarbon receptor (AHR) and its target gene CYP1B1 and to correlate their expression with Wnt5a/b-β-catenin, the CD44(+)/CD24((−/low)) cancer stem cell (CSC) subset and factors associated with poor prognosis in inflamm...

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Detalhes bibliográficos
Publicado no:J Adv Res
Main Authors: Mohamed, Hossam T., Gadalla, Ramy, El-Husseiny, Noura, Hassan, Hebatallah, Wang, Zhongyan, Ibrahim, Sherif A., El-Shinawi, Mohamed, Sherr, David H., Mohamed, Mona M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413307/
https://ncbi.nlm.nih.gov/pubmed/30899591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2018.11.006
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