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Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol
LAT1 (SLC7A5) is a transporter for both the uptake of large neutral amino acids and a number of pharmaceutical drugs. It is expressed in numerous cell types including T-cells, cancer cells and brain endothelial cells. However, mechanistic knowledge of how it functions and its interactions with lipid...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341093/ https://ncbi.nlm.nih.gov/pubmed/28272458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43580 |
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