Pharmacokinetics and Bioavailability of the GnRH Analogs in the Form of Solution and Zn(2+)-Suspension After Single Subcutaneous Injection in Female Rats

BACKGROUND AND OBJECTIVES: Although many synthetic gonadoliberin analogs have been developed, only a few of them, including buserelin, were introduced into clinical practice. Dalarelin, which differs from buserelin by just one aminoacid in the position 6 (D-Ala), is not widely used so far. Gonadotro...

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Bibliografiske detaljer
Udgivet i:Eur J Drug Metab Pharmacokinet
Main Authors: Suszka-Świtek, Aleksandra, Ryszka, Florian, Dolińska, Barbara, Dec, Renata, Danch, Alojzy, Filipczyk, Łukasz, Wiaderkiewicz, Ryszard
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340827/
https://ncbi.nlm.nih.gov/pubmed/27180066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-016-0342-5
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