Analysis of the Serotonergic System in a Mouse Model of Rett Syndrome Reveals Unusual Upregulation of Serotonin Receptor 5b

Mutations in the transcription factor methyl-CpG-binding-protein 2 (MeCP2) cause a delayed-onset neurodevelopmental disorder known as Rett syndrome (RTT). Although alteration in serotonin levels have been reported in RTT patients, the molecular mechanisms underlying these defects are not well unders...

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Опубликовано в: :Front Mol Neurosci
Главные авторы: Vogelgesang, Steffen, Niebert, Sabine, Renner, Ute, Möbius, Wiebke, Hülsmann, Swen, Manzke, Till, Niebert, Marcus
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340760/
https://ncbi.nlm.nih.gov/pubmed/28337123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00061
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