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Down-regulation of mediator complex subunit 19 (Med19) induces apoptosis in human laryngocarcinoma HEp2 cells in an Apaf-1-dependent pathway

Mediator 19 (Med19) is a component of the mediator complex which is a co-activator for DNA-binding factors that activate transcription via RNA polymerase II. Accumulating evidence has shown that Med19 plays important roles in cancer cell proliferation and tumorigenesis. The physiological mechanism b...

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Bibliografische gegevens
Gepubliceerd in:Am J Transl Res
Hoofdauteurs: Zhao, Yan, Meng, Qingfeng, Gao, Xu, Zhang, Lihua, An, Lixin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340711/
https://ncbi.nlm.nih.gov/pubmed/28337304
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