Characterization of a Biflaviolin Synthase CYP158A3 from Streptomyces avermitilis and Its Role in the Biosynthesis of Secondary Metabolites

Streptomyces avermitilis produces clinically useful drugs such as avermectins and oligomycins. Its genome contains approximately 33 cytochrome P450 genes and they seem to play important roles in the biosynthesis of many secondary metabolites. The SAV_7130 gene from S. avermitilis encodes CYP158A3. T...

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Publicat a:Biomol Ther (Seoul)
Autors principals: Lim, Young-Ran, Han, Songhee, Kim, Joo-Hwan, Park, Hyoung-Goo, Lee, Ga-Young, Le, Thien-Kim, Yun, Chul-Ho, Kim, Donghak
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society of Applied Pharmacology 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340542/
https://ncbi.nlm.nih.gov/pubmed/27956713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.182
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