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Dynamics and Fate of Beneficial Mutations Under Lineage Contamination by Linked Deleterious Mutations
Beneficial mutations drive adaptive evolution, yet their selective advantage does not ensure their fixation. Haldane’s application of single-type branching process theory showed that genetic drift alone could cause the extinction of newly arising beneficial mutations with high probability. With link...
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| Publicado no: | Genetics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5340340/ https://ncbi.nlm.nih.gov/pubmed/28100591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.194597 |
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