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The Fates of Mutant Lineages and the Distribution of Fitness Effects of Beneficial Mutations in Laboratory Budding Yeast Populations

The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting microbial populations, this process is particularly hard to predict because lineages with different beneficial mutations often spread simultaneously and interfere with one another’s fixation. Hence to pred...

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Autores principales: Frenkel, Evgeni M., Good, Benjamin H., Desai, Michael M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982683/
https://ncbi.nlm.nih.gov/pubmed/24514901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.160069
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