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A Robust and Powerful Set-Valued Approach to Rare Variant Association Analyses of Secondary Traits in Case-Control Sequencing Studies

In many case-control designs of genome-wide association (GWAS) or next generation sequencing (NGS) studies, extensive data on secondary traits that may correlate and share the common genetic variants with the primary disease are available. Investigating these secondary traits can provide critical in...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Kang, Guolian, Bi, Wenjian, Zhang, Hang, Pounds, Stanley, Cheng, Cheng, Shete, Sanjay, Zou, Fei, Zhao, Yanlong, Zhang, Ji-Feng, Yue, Weihua
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340322/
https://ncbi.nlm.nih.gov/pubmed/28040743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.192377
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