An optimized IFN-γ ELISpot assay for the sensitive and standardized monitoring of CMV protein-reactive effector cells of cell-mediated immunity

BACKGROUND: In healthy individuals, Cytomegalovirus (CMV) infection is efficiently controlled by CMV-specific cell-mediated immunity (CMI). Functional impairment of CMI in immunocompromized individuals however can lead to uncontrolled CMV replication and severe clinical complications. Close monitori...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Barabas, Sascha, Spindler, Theresa, Kiener, Richard, Tonar, Charlotte, Lugner, Tamara, Batzilla, Julia, Bendfeldt, Hanna, Rascle, Anne, Asbach, Benedikt, Wagner, Ralf, Deml, Ludwig
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339961/
https://ncbi.nlm.nih.gov/pubmed/28270111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0195-y
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