A proteomic approach to identify endosomal cargoes controlling cancer invasiveness

We have previously shown that Rab17, a small GTPase associated with epithelial polarity, is specifically suppressed by ERK2 (also known as MAPK1) signalling to promote an invasive phenotype. However, the mechanisms through which Rab17 loss permits invasiveness, and the endosomal cargoes that are res...

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Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Diaz-Vera, Jesica, Palmer, Sarah, Hernandez-Fernaud, Juan Ramon, Dornier, Emmanuel, Mitchell, Louise E., Macpherson, Iain, Edwards, Joanne, Zanivan, Sara, Norman, Jim C.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339883/
https://ncbi.nlm.nih.gov/pubmed/28062852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.190835
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