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Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes
Fyn tyrosine kinase has been implicated in the pathogenesis of Alzheimer’s disease (AD). We have previously reported that upregulation of the FynT isoform in AD brains was partly associated with astrocyte activation. In this study, we demonstrated selective FynT induction in murine cortex and primar...
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| Yayımlandı: | Sci Rep |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339870/ https://ncbi.nlm.nih.gov/pubmed/28266558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43651 |
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