Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos

Thyroid hormones are essential for normal brain development in vertebrates. In humans, abnormal maternal thyroid hormone levels during early pregnancy are associated with decreased offspring IQ and modified brain structure. As numerous environmental chemicals disrupt thyroid hormone signalling, we q...

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Publicado no:Sci Rep
Main Authors: Fini, Jean-Baptiste, Mughal, Bilal B., Le Mével, Sébastien, Leemans, Michelle, Lettmann, Mélodie, Spirhanzlova, Petra, Affaticati, Pierre, Jenett, Arnim, Demeneix, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339866/
https://ncbi.nlm.nih.gov/pubmed/28266608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43786
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