The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter

The serotonin transporter (SERT) and other monoamine transporters operate in either a forward transport mode where the transporter undergoes a full transport cycle or an exchange mode where the transporter seesaws through half-cycles. Amphetamines trigger the exchange mode, leading to substrate effl...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Kern, Carina, Erdem, Fatma Asli, El-Kasaby, Ali, Sandtner, Walter, Freissmuth, Michael, Sucic, Sonja
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339746/
https://ncbi.nlm.nih.gov/pubmed/28104804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771360
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