Restoration of NF-κB Activation by Tumor Necrosis Factor Alpha Receptor Complex-Targeted MEKK3 in Receptor-Interacting Protein-Deficient Cells

Receptor-interacting protein (RIP) plays a critical role in tumor necrosis factor alpha (TNF-α)-induced NF-κB activation. However, the mechanism by which RIP mediates TNF-α-induced signal transduction is not fully understood. In this study, we reconstituted RIP-deficient Jurkat T cells with a fusion...

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Hlavní autoři: Blonska, Marzenna, You, Yun, Geleziunas, Romas, Lin, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC533972/
https://ncbi.nlm.nih.gov/pubmed/15572679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10757-10765.2004
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