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Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE
Modelling Down syndrome (DS) in mouse has been crucial for the understanding of the disease and the evaluation of therapeutic targets. Nevertheless, the modelling so far has been limited to the mouse and, even in this model, generating duplication of genomic regions has been labour intensive and tim...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339700/ https://ncbi.nlm.nih.gov/pubmed/28266534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43331 |
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