Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

Pancreatic stellate cells (PSCs) differentiate into cancer-associated fibroblasts (CAFs) that produce desmoplastic stroma, thereby modulating disease progression and therapeutic response in pancreatic ductal adenocarcinoma (PDA). However, it is unknown whether CAFs uniformly carry out these tasks or...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Öhlund, Daniel, Handly-Santana, Abram, Biffi, Giulia, Elyada, Ela, Almeida, Ana S., Ponz-Sarvise, Mariano, Corbo, Vincenzo, Oni, Tobiloba E., Hearn, Stephen A., Lee, Eun Jung, Chio, Iok In Christine, Hwang, Chang-Il, Tiriac, Hervé, Baker, Lindsey A., Engle, Dannielle D., Feig, Christine, Kultti, Anne, Egeblad, Mikala, Fearon, Douglas T., Crawford, James M., Clevers, Hans, Park, Youngkyu, Tuveson, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339682/
https://ncbi.nlm.nih.gov/pubmed/28232471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20162024
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge