ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans

Nonimmunological connective tissue phenotypes in humans are common among some congenital and acquired allergic diseases. Several of these congenital disorders have been associated with either increased TGF-β activity or impaired STAT3 activation, suggesting that these pathways might intersect and th...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Lyons, J.J., Liu, Y., Ma, C.A., Yu, X., O’Connell, M.P., Lawrence, M.G., Zhang, Y., Karpe, K., Zhao, M., Siegel, A.M., Stone, K.D., Nelson, C., Jones, N., DiMaggio, T., Darnell, D.N., Mendoza-Caamal, E., Orozco, L., Hughes, J.D., McElwee, J., Hohman, R.J., Frischmeyer-Guerrerio, P.A., Rothenberg, M.E., Freeman, A.F., Holland, S.M., Milner, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339676/
https://ncbi.nlm.nih.gov/pubmed/28126831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161435
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